Gamete Intrafallopian Transfer (GIFT)

The GIFT procedure is one of 3 advanced «tubal transfer» minimally invasive laparoscopic procedures aimed at maximizing your fertility potential through assisted reproductive technology (ART): GIFT, ZIFT, and TET. Laparoscopic tubal transfer (intrafallopian transfer) allows for the transfer of gametes (eggs and sperm) or early-stage embryos (day 1 zygotes or day 2 cleavage-stage embryos) directly into the fallopian tube(s). Embryos conceived and/or grown in the fallopian tube have the advantage of being in their natural environment, the tube, at the critical early stages of their development, making the tube the optimal «incubator» for embryo culture to the blastocyst stage. In fact, prior to the advent of advanced culture solutions in the IVF laboratory, tubal transfer achieved superior pregnancy success rates over standard IVF. However, as IVF technology evolved, improved IVF culture conditions and techniques allowing embryos to be grown from day 0 to day 6 in the IVF laboratory and the less invasive nature of IVF, favored the IVF lab over the fallopian tube as the preferred site for early embryo development.

Today, the role of tubal transfer has been reestablished in ART for specific clinical scenarios. Despite improvements in standard IVF techniques, some couples may experience IVF failure due to poor embryo development in the laboratory. This may manifest itself with poor development at the cleavage stage (failure of embryos to reach the 6-8 cell stage by day 3 after egg retrieval, or poor quality embryos on day 3 despite reaching the 6-8 cell stage), or at the blastocyst stage (failure of embryos to reach the blastocyst stage by day 5 after egg retrieval, or poor quality blastocysts on day 5). For such couples, after repeated IVF and standard trans-cervical embryo transfer (IVF/ET) failure, transferring eggs and sperm or early embryos directly into their natural environment, the fallopian tube, may be the ideal solution. For some couples, a clear explanation for repeated implantation failure after routine trans-cervical embryo transfer of good quality day 3 or day 5 embryos may not exist, making a GIFT, ZIFT, or TET an excellent alternative as means of improving embryo implantation rates. Additionally, for some women, prior cervical surgery (LEEP procedure or cervical conization for abnormal Pap smear) or damage to the cervix following various gynecological procedures, or a congenital birth defect affecting the cervix, may make a standard trans-cervical embryo transfer following IVF impossible or exceedingly difficult. In such cases, bypassing the cervix with a tubal transfer technique is the preferred choice when performing ART.

In a GIFT procedure, patients first undergo standard controlled ovarian hyperstimulation (COH = ovarian stimulation with injectable hormones to stimulate the growth of multiple eggs) followed by egg retrieval. Immediately following egg retrieval, while still under anesthesia in the operating room, a laparoscopy is performed by introducing a small camera through an umbilical incision (typically smaller than 5 mm in length) to visualize the pelvic contents. A second small incision is introduced above the pubic bone (suprapubic) in the lower abdomen, which allows for the insertion of a non-traumatic grasping instrument for gentle manipulation of the fallopian tube. Finally, a third 2 mm incision is introduced between the umbilical and suprapubic incisions, which allows insertion of a small catheter (containing eggs and sperm) into the pelvic region. Under direct visualization with the laparoscope, the fallopian tube is grasped with forceps and the midline catheter is advanced into the distal opening of the tube. Next, 1-2 eggs mixed with thousands of sperm are deposited into the distal portion of the tube. The tube is gently placed back into its anatomical location. The procedure may be repeated on the opposite tube.

The entire procedure (egg retrieval + GIFT) is typically completed in less than 45 minutes, which allows for rapid recovery without the need for bed rest. GIFT relies on the ability of sperm to naturally fertilize eggs and is therefore not suitable for couples with male factor infertility. Naturally, all tubal transfer techniques rely on healthy fallopian tubes for a successful outcome.

The California Center for Reproductive Health employs nothing but the finest expert microsurgical techniques in performing laparoscopic GIFT procedures, providing for safe and effective surgical treatments with excellent outcome.

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Eliran Mor, MD • Encino, Santa Monica, Valencia & West Hollywood, CA

Reproductive Endocrinologist located in Encino, Santa Monica, Valencia & West Hollywood, CA • Irene Woo, MD

Doctor Mor received his medical degree from Tel Aviv University-Sackler School of Medicine in Israel. He completed a four-year residency in Obstetrics and Gynecology at New York Methodist Hospital in Brooklyn, New York. Subsequently, Dr. Mor completed a three-year fellowship in Reproductive Endocrinology and Infertility at the University of Southern California. Doctor Mor is Board Certified in both Reproductive Endocrinology/Infertility and Obstetrics and Gynecology. Throughout his career Dr. Mor has researched many topics in infertility and human reproduction, including polycystic ovary syndrome (PCOS); emergency contraception; neuroendocrinology; insulin resistance; male factor infertility; donor sperm insemination; tubal factor infertility; IVF stimulation protocols; congenital uterine anomalies; tubal gamete/embryo transfer (GIFT/ZIFT/TET); pregnancy at advanced reproductive age; and hormone replacement therapy (HRT), and continues to do so today. He is a member, in excellent standing, of multiple prestigious medical societies, including the American Society of Reproductive Medicine (ASRM), the Pacific Coast Reproductive Society (PCRS), the Society of Laparoendoscopic Surgeons (SLS), and the American College of Obstetricians and Gynecologists (ACOG), and remains a Clinical Instructor at USC.

Doctor Mor is one fertility expert who is constantly striving to stay on the cutting-edge of fertility treatments and human reproduction. In addition to monthly Journal Club meetings/publication review sessions and educational seminars/lectures, Dr. Mor attends at least two major Reproductive Endocrinology/Infertility meetings each year in an effort to present his patients with the latest in innovative reproductive care. Only interventions that have been tested and validated through multiple good studies are adopted in Dr. Mor’s practice, in an effort to administer safe and effective treatments to achieve a healthy pregnancy.

A true “patients’ doctor,” Dr. Mor is and will be your physician throughout your fertility journey! All consultations, after-hour inquiries, pelvic examinations, ultrasound examinations, diagnostic procedures, assisted reproductive procedures (egg retrievals, embryo transfers...), and surgical procedures, if needed, will be performed by Dr. Mor. Involvement in every aspect of your fertility care and complete micromanagement of your treatment makes Dr. Mor your ideal partner in your path to becoming pregnant.

See Dr. Mor's Publications

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California Center for Reproductive Health

Doctor Mor received his medical degree from Tel Aviv University-Sackler School of Medicine in Israel. He completed a four-year residency in Obstetrics and Gynecology at New York Methodist Hospital in Brooklyn, New York. Subsequently, Dr. Mor completed a three-year fellowship in Reproductive Endocrinology and Infertility at the University of Southern California. Doctor Mor is Board Certified in both Reproductive Endocrinology/Infertility and Obstetrics and Gynecology. Throughout his career Dr. Mor has researched many topics in infertility and human reproduction, including polycystic ovary syndrome (PCOS); emergency contraception; neuroendocrinology; insulin resistance; male factor infertility; donor sperm insemination; tubal factor infertility; IVF stimulation protocols; congenital uterine anomalies; tubal gamete/embryo transfer (GIFT/ZIFT/TET); pregnancy at advanced reproductive age; and hormone replacement therapy (HRT), and continues to do so today. He is a member, in excellent standing, of multiple prestigious medical societies, including the American Society of Reproductive Medicine (ASRM), the Pacific Coast Reproductive Society (PCRS), the Society of Laparoendoscopic Surgeons (SLS), and the American College of Obstetricians and Gynecologists (ACOG), and remains a Clinical Instructor at USC.

Doctor Mor is one fertility expert who is constantly striving to stay on the cutting-edge of fertility treatments and human reproduction. In addition to monthly Journal Club meetings/publication review sessions and educational seminars/lectures, Dr. Mor attends at least two major Reproductive Endocrinology/Infertility meetings each year in an effort to present his patients with the latest in innovative reproductive care. Only interventions that have been tested and validated through multiple good studies are adopted in Dr. Mor’s practice, in an effort to administer safe and effective treatments to achieve a healthy pregnancy.

A true “patients’ doctor,” Dr. Mor is and will be your physician throughout your fertility journey! All consultations, after-hour inquiries, pelvic examinations, ultrasound examinations, diagnostic procedures, assisted reproductive procedures (egg retrievals, embryo transfers...), and surgical procedures, if needed, will be performed by Dr. Mor. Involvement in every aspect of your fertility care and complete micromanagement of your treatment makes Dr. Mor your ideal partner in your path to becoming pregnant.

See Dr. Mor's Publications


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We invite you to join our family as we look to expand yours!

Doctor Mor is a Board Certified Reproductive Endocrinology/Infertility expert with extensive experience in the most advanced fertility treatments available. Under his leadership, CCRH has become renowned for superior reproductive care, receiving rave reviews year after year. The Center is a boutique practice with exceptionally personalized service, customized and individually-tailored to each person or couple's needs with unmatched results.

Great emphasis is placed on proper testing and accurate
diagnosis, allowing for safe and effective treatments to achieve the ultimate outcome – a healthy baby!

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Professional Affiliations/Resources

The physicians and staff of the California Center for Reproductive Health are dedicated to patient education and care. The Center is affiliated with several prestigious medical societies and organizations aimed at educating both healthcare professionals and patients and at improving patient care. The following is a list of professional affiliations:

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Testimonials

Words from our patients

  • Healthgrades

    "Dr. Mor has helped my wife and I get pregnant. He is an expert in his field with a wealth of knowledge which he personalized for our individual situation."

    Gilbert
  • Healthgrades

    "Dr. Mor is a phenomenal human being with a wealth of knowledge. From our first appointment to our last, he demonstrated his great bed side manner."

    Veronica
  • Dear CCRH Team, thank you for all the support in my journey to get pregnant. My twins are blessed without a deadly cancer gene and all of you made it happen.

    A.A.
  • You are a wonderful doctor and a very nice person. The babies are doing great and our family is very happy. M.L.

    M.L.
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